Unique k-mer sequences for validating cancer-related substitution, insertion and deletion mutations
نویسندگان
چکیده
منابع مشابه
An analysis of substitution, deletion and insertion mutations in cancer genes
Cancer-associated mutations in cancer genes constitute a diverse set of mutations associated with the disease. To gain insight into features of the set, substitution, deletion and insertion mutations were analysed at the nucleotide level, from the COSMIC database. The most frequent substitutions were c → t, g → a, g → t, and the most frequent codon changes were to termination codons. Deletions ...
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A number of methods have been proposed over the last decade for embedding information within deoxyribonucleic acid (DNA). Since a DNA sequence is conceptually equivalent to a unidimensional digital signal, DNA data embedding (diversely called DNA watermarking or DNA steganography) can be seen either as a traditional communications problem or as an instance of communications with side informatio...
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The operation of k−insertion (k−deletion) is a generalization of the catenation (quotient) of words and languages. The k−insertion of w into u = u1u2 consists of all words u1wu2 where the length of u2 is at most k (k−deletion is performed in a analogous fashion). To a language L we associate the set k−ins(L) (k−del(L)) consisting of words with the following property: their k−insertion into (k−d...
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ژورنال
عنوان ژورنال: NAR Cancer
سال: 2020
ISSN: 2632-8674
DOI: 10.1093/narcan/zcaa034